Friday, January 21, 2011

Regulation of Blood Cell Differentiation

Another cause for celebration. A project that was active for several years has made it to publication. Today a paper with Noa as a first author appeared in Cell. This project was mostly done when Noa was at Aviv Regev's lab at the Broad Institute. She analyzed the expression profiles of genes through the differentiation of hematopoitic cell lineages --- how a bone marrow stem cell develops in to different types of blood cells.

                                                                          (Source: Cell)

The interesting part is that this analysis uncovered multiple "modules" --- groups of genes --- that are reused in different lineages. This shows that differentiation is much more complex than previously assumed about this system.

Congratulations to Noa!

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